Priority interventions for a postoperative client include monitoring vital signs, pain assessment, and neurological and wound evaluation. Pharmacological interventions focus on pain management and fluid balance, while non-pharmacological measures include ice therapy, positioning, and ambulation. Patient comfort and support involve managing bowel function, providing emotional support, and ensuring adequate nutrition. Wound management encompasses dressing changes, irrigation, and antibiotics. Care also includes blood glucose monitoring, medication administration, infection prevention, and early detection of complications.