Blood clotting is a crucial process that prevents excessive bleeding in horses. Various factors influence blood vessel clogging in horses, including the concentration and shape of red blood cells, the levels of plasma proteins like fibrinogen, and the presence of antibodies that bind to red blood cells. These factors interact to determine the likelihood of blood clots forming, affecting overall equine health. Understanding the mechanisms of blood clotting and the influential factors involved is essential for assessing and managing clotting-related disorders in horses.